Rho-kinase (ROCK) inhibition, widely used in cardiovascular disease, could protect the blood-brain barrier (BBB) from damage during thrombolysis rt-PA-induced. While the use of inhibitors of ROCK nonselective as fasudil together with rt-PA can be deterred by the possibility of hypotension side effects and inadequate capacity to block the activity of rt-PA detrimental to endothelial cells of the brain (BEC), a selective ROCK-2 inhibition may overcome these limitations , Here, we examine ROCK-2 expression in primary brain cells and compare the ability of fasudil and KD 025, a selective ROCK-2 inhibitor, to attenuate the rt-PA-induced BBB disruption in vitro human models.
ROCK-2 highly expressed relative to ROCK-1 in all kinds of human and mouse brain cells and particularly enriched in rat brain endothelial cells and astrocytes compared to neurons. KD 025 is stronger than fasudil in attenuation of rt-PA-induced plasminogen-and permeation BBB under normoxia, but especially under conditions such as stroke. Importantly, only KD 025, but not fasudil, was able to block the increase in the permeability of rt-PA-dependent, changes in morphology and tight junction degradation in BECs isolated.
Selective inhibition of ROCK-2 further diminished rt-PA-induced phosphorylation of myosin, transformation and activation of matrix metalloprotease in astrocytes. These findings highlight the isoforms ROCK-2 as the main driving BBB endothelial disorders and brain damage by rt-PA and the potential of KD 025 to optimally protect the BBB during thrombolysis.
Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin.
Evaluation fibrinolytic Inhibitors : alpha- two -Antiplasmin and Plasminogen Activator inhibitors 1 patients with Obstructive Sleep Apnea.
Obstructive sleep apnea (OSA) inducing thrombophilia and reduced fibrinolysis. Alpha-2-antiplasmin (a-2-AP) and plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system. Increasing concentrations of this factor is associated with a higher risk of cardiovascular disease. The purpose of this study was to evaluate plasma-2-AP and PAI-1 in patients with OSA and evaluate the correlation with polysomnographic records and selected risk factors of cardiovascular disease.
The study group comprised 45 patients with OSA, and the control group consisted of 19 patients who did not meet the diagnostic criteria of OSA. Plasma-2-AP and PAI-1 concentrations assessed by enzyme-linked immunosorbent assay (ELISA). In the study group, the median value of plasma-2-AP is higher than the control group (11.89 vs 157.34 pg / ml, respectively, P <0.0001). A-2-AP concentration increases proportionally with the severity of OSA.
The concentration of 2-AP positively correlated with the index of apnea-hypopnoea (AHI), apnea index (AI), respiratory disturbance time (RDT), and the index desaturaion (DI), and negatively correlated with oxygen saturation, mean and minimum (SpO2 means, SpO2 min, respectively). The median value of PAI-1 was higher in the study group than the control group (12.55 vs. 5.40 ng / ml, respectively, P = 0.006) and increased with the severity of OSA. PAI-1 concentrations correlated positively with AHI, AI, RDT, DI, and body mass index (BMI) and negatively correlated with mean SpO2 and SpO2 min.
Higher plasma concentrations of 2-AP and PAI-1 in patients with OSA showed that these patients had increased prothrombotic activity. OSA increases the risk of cardiovascular complications such as increased prothrombotic activity.
Recombinant Mouse Plasminogen Activator Inhibitor-2
MBS146819-1mg
MyBiosource
1mg
EUR 5345
Recombinant Mouse Plasminogen Activator Inhibitor-2
MBS146819-5x1mg
MyBiosource
5x1mg
EUR 23725
Plasminogen Activator Inhibitor-2 Mouse Recombinant
rAP-1489
Angio Proteomie
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Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 320
Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 320
Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 520
Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 515
Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-05mgYeast
MyBiosource
0.5mg(Yeast)
EUR 1260
Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-002mg
MyBiosource
0.02mg
EUR 380
Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-01mg
MyBiosource
0.1mg
EUR 650
Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-1mg
MyBiosource
1mg
EUR 2525
Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-5x1mg
MyBiosource
5x1mg
EUR 11205
Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
CSB-YP021081MO
Cusabio
5989 mg
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Recombinant Mouse Plasminogen activator inhibitor 1(Serpine1)
AP70764
SAB
1mg
EUR 2826
Recombinant Mouse Plasminogen activator inhibitor 1(Serpine1)
AP72777
SAB
each
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Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
CSB-EP021081MO
Cusabio
2166 mg
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Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC21989-100ug
Biomatik Corporation
100ug
EUR 705.1
Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC21989-1mg
Biomatik Corporation
1mg
EUR 3237
Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC21989-20ug
Biomatik Corporation
20ug
EUR 353.4
Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC24943-100ug
Biomatik Corporation
100ug
EUR 702.9
Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC24943-20ug
Biomatik Corporation
20ug
EUR 353.4
SERPINE2 Plasminogen Activator Inhibitor-2 Mouse Recombinant Protein
PROTQ07235
BosterBio
Regular: 10ug
EUR 380.4
Description: SERPINE2 produced in Sf9 Baculovirus cells is a single,glycosylated polypeptide chain containing 386 amino acids (20-397a.a.) andhaving a molecular mass of 42.9kDa (Molecular size on SDS-PAGE will appear atapproximately 40-57kDa).SERPINE2 is expressed with a 8 amino acid His tag atC-Terminus and purified by proprietary chromatographic techniques.
Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-002mgBaculovirus
MyBiosource
0.02mg(Baculovirus)
EUR 1285
Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 965
Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 1080
Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 1125
Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 1230
Recombinant Human Plasminogen Activator Inhibitor-2
AP60417
SAB
100ug
EUR 1554
Recombinant Human Plasminogen Activator Inhibitor-2
P1567-.01
ApexBio
10ug
EUR 272.8
Description: Peptides & Proteins|Recombinant Proteins
Recombinant Human Plasminogen Activator Inhibitor-2
P1567-.1
ApexBio
100ug
EUR 1560.8
Description: Peptides & Proteins|Recombinant Proteins
Recombinant Human Plasminogen Activator Inhibitor-2
P1567-.5
ApexBio
500ug
EUR 3503.2
Description: Peptides & Proteins|Recombinant Proteins
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU56751-100ug
Biomatik Corporation
100ug
EUR 470.4
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU56751-50ug
Biomatik Corporation
50ug
EUR 385
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43313-100ug
Biomatik Corporation
100ug
EUR 524.7
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43313-1mg
Biomatik Corporation
1mg
EUR 2325.7
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43313-50ug
Biomatik Corporation
50ug
EUR 421.3
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43314-100ug
Biomatik Corporation
100ug
EUR 562.1
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43314-1mg
Biomatik Corporation
1mg
EUR 2489.5
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43314-50ug
Biomatik Corporation
50ug
EUR 451
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43315-100ug
Biomatik Corporation
100ug
EUR 599.5
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43315-1mg
Biomatik Corporation
1mg
EUR 2653.3
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43315-50ug
Biomatik Corporation
50ug
EUR 480.7
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPA531Hu01
Cloud-Clone
10ug
EUR 170
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
4-RPA531Hu01
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Human Plasminogen Activator Inhibitor 2 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPA531Mu01
Cloud-Clone
10ug
EUR 182
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
4-RPA531Mu01
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Mouse Plasminogen Activator Inhibitor 2 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPA531Ra01
Cloud-Clone
10ug
EUR 194
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
4-RPA531Ra01
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Rat Plasminogen Activator Inhibitor 2 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-001mg
MyBiosource
0.01mg
EUR 180
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-005mg
MyBiosource
0.05mg
EUR 330
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-01mg
MyBiosource
0.1mg
EUR 500
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-02mg
MyBiosource
0.2mg
EUR 615
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-05mg
MyBiosource
0.5mg
EUR 1170
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-001mg
MyBiosource
0.01mg
EUR 175
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-005mg
MyBiosource
0.05mg
EUR 315
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-01mg
MyBiosource
0.1mg
EUR 475
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-02mg
MyBiosource
0.2mg
EUR 580
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-05mg
MyBiosource
0.5mg
EUR 1100
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-001mg
MyBiosource
0.01mg
EUR 170
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-005mg
MyBiosource
0.05mg
EUR 295
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-01mg
MyBiosource
0.1mg
EUR 450
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-02mg
MyBiosource
0.2mg
EUR 545
Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-05mg
MyBiosource
0.5mg
EUR 1040
Recombinant human Plasminogen activator inhibitor 2
P1738
FN Test
100ug
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Description: Recombinant protein for human Plasminogen activator inhibitor 2
Plasminogen Activator Inhibitor-1 (Recombinant)
20-abx073514
Abbexa
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Plasminogen Activator Inhibitor Type 1, Recombinant, Mouse (PAI-1)
MBS636215-05mg
MyBiosource
0.5mg
EUR 1895
Plasminogen Activator Inhibitor Type 1, Recombinant, Mouse (PAI-1)
MBS636215-5x05mg
MyBiosource
5x0.5mg
EUR 8310
Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 320
Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 520
Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-1mgEColi
MyBiosource
1mg(E-Coli)
EUR 1925
Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-5x1mgEColi
MyBiosource
5x1mg(E-Coli)
EUR 8405
Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-002mg
MyBiosource
0.02mg
EUR 380
Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-01mg
MyBiosource
0.1mg
EUR 650
Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-1mg
MyBiosource
1mg
EUR 2525
Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-5x1mg
MyBiosource
5x1mg
EUR 11205
Plasminogen Activator Inhibitor-1 Human Recombinant
rAP-4753
Angio Proteomie
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Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-0005mg
MyBiosource
0.005mg
EUR 240
Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-0025mg
MyBiosource
0.025mg
EUR 310
Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-1mg
MyBiosource
1mg
EUR 3165
Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-5x1mg
MyBiosource
5x1mg
EUR 13925
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU55545-100ug
Biomatik Corporation
100ug
EUR 601.7
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU55545-1mg
Biomatik Corporation
1mg
EUR 2371.2
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU55545-50ug
Biomatik Corporation
50ug
EUR 364.8
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU56752-100ug
Biomatik Corporation
100ug
EUR 470.4
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU56752-50ug
Biomatik Corporation
50ug
EUR 385
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU52990-100ug
Biomatik Corporation
100ug
EUR 542.3
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU52990-1mg
Biomatik Corporation
1mg
EUR 2402.4
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU52990-50ug
Biomatik Corporation
50ug
EUR 435.6
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU51492-100ug
Biomatik Corporation
100ug
EUR 492.8
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU51492-50ug
Biomatik Corporation
50ug
EUR 396
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU43312-100ug
Biomatik Corporation
100ug
EUR 468.6
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU43312-1mg
Biomatik Corporation
1mg
EUR 2074.8
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU43312-50ug
Biomatik Corporation
50ug
EUR 376.2
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Hu01
Cloud-Clone
10ug
EUR 152
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Hu01
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Human Plasminogen Activator Inhibitor 1 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Hu02
Cloud-Clone
10ug
EUR 152
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Hu02
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Human Plasminogen Activator Inhibitor 1 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Mu01
Cloud-Clone
10ug
EUR 160
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Mu01
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Mouse Plasminogen Activator Inhibitor 1 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Ra01
Cloud-Clone
10ug
EUR 176
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Ra01
Cloud-Clone
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100 ug
10ug
1 mg
200 ug
500 ug
50ug
5 mg
Description: Recombinant Rat Plasminogen Activator Inhibitor 1 expressed in: E.coli
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Si01
Cloud-Clone
10ug
EUR 164
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-001mg
MyBiosource
0.01mg
EUR 165
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-005mg
MyBiosource
0.05mg
EUR 285
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-01mg
MyBiosource
0.1mg
EUR 425
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-02mg
MyBiosource
0.2mg
EUR 515
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-05mg
MyBiosource
0.5mg
EUR 980
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-001mg
MyBiosource
0.01mg
EUR 170
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-005mg
MyBiosource
0.05mg
EUR 305
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-01mg
MyBiosource
0.1mg
EUR 460
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-02mg
MyBiosource
0.2mg
EUR 560
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-05mg
MyBiosource
0.5mg
EUR 1065
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-001mg
MyBiosource
0.01mg
EUR 160
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-005mg
MyBiosource
0.05mg
EUR 280
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-01mg
MyBiosource
0.1mg
EUR 405
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-02mg
MyBiosource
0.2mg
EUR 490
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-05mg
MyBiosource
0.5mg
EUR 930
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-001mg
MyBiosource
0.01mg
EUR 160
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-005mg
MyBiosource
0.05mg
EUR 280
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-01mg
MyBiosource
0.1mg
EUR 405
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-02mg
MyBiosource
0.2mg
EUR 490
Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-05mg
MyBiosource
0.5mg
EUR 930
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
CSB-YP021070HU
Cusabio
5987 mg
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Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
CSB-MP021070HU
Cusabio
4968 mg
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Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
RPC26411-100ug
Biomatik Corporation
100ug
EUR 1218.8
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
RPC26411-20ug
Biomatik Corporation
20ug
EUR 484
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-002mgMammalianCell
MyBiosource
0.02mg(Mammalian-Cell)
EUR 425
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 320
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-01mgMammalianCell
MyBiosource
0.1mg(Mammalian-Cell)
EUR 1015
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 515
Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-05mgYeast
MyBiosource
0.5mg(Yeast)
EUR 1260
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-002mg
MyBiosource
0.02mg
EUR 380
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-01mg
MyBiosource
0.1mg
EUR 650
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-05mg
MyBiosource
0.5mg
EUR 1655
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-5x05mg
MyBiosource
5x0.5mg
EUR 7290
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-002mg
MyBiosource
0.02mg
EUR 380
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-01mg
MyBiosource
0.1mg
EUR 650
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-1mg
MyBiosource
1mg
EUR 2525
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-5x1mg
MyBiosource
5x1mg
EUR 11205
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 320
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-002mgYeast
MyBiosource
0.02mg(Yeast)
EUR 320
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 520
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-01mgYeast
MyBiosource
0.1mg(Yeast)
EUR 515
Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-05mgYeast
MyBiosource
0.5mg(Yeast)
EUR 1260
Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-002mgEColi
MyBiosource
0.02mg(E-Coli)
EUR 255
Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-01mgEColi
MyBiosource
0.1mg(E-Coli)
EUR 405
Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-1mgEColi
MyBiosource
1mg(E-Coli)
EUR 1425
Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-5x1mgEColi
MyBiosource
5x1mg(E-Coli)
EUR 6215
Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-002mg
MyBiosource
0.02mg
EUR 285
Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-01mg
MyBiosource
0.1mg
EUR 470
Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-1mg
MyBiosource
1mg
EUR 1785
Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-5x1mg
MyBiosource
5x1mg
EUR 7885
Recombinant human Plasminogen activator inhibitor 1
MBS961954-005mg
MyBiosource
0.05mg
EUR 260
Recombinant human Plasminogen activator inhibitor 1
MBS961954-02mg
MyBiosource
0.2mg
EUR 560
Recombinant human Plasminogen activator inhibitor 1
MBS961954-05mg
MyBiosource
0.5mg
EUR 875
Recombinant human Plasminogen activator inhibitor 1
MBS961954-1mg
MyBiosource
1mg
EUR 1325
Mouse Plasminogen Activator Inhibitor 2 ELISA kit
E01A24356
BlueGene
96T
EUR 700
Description: ELISA
Mouse Plasminogen Activator Inhibitor 2 ELISA kit
E03P0057-192T
BlueGene
192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Plasminogen Activator Inhibitor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Plasminogen Activator Inhibitor 2 ELISA kit
E03P0057-48
BlueGene
1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Plasminogen Activator Inhibitor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Plasminogen Activator Inhibitor 2 ELISA kit
E03P0057-96
BlueGene
1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Plasminogen Activator Inhibitor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Plasminogen Activator Inhibitor 2 ELISA Kit
MBS020364-10x96StripWells
MyBiosource
10x96-Strip-Wells
EUR 6725
A significant effect of rs2070682 in the risk of early onset DR found in codominant model of inheritance [odds ratio, OR (95% confidence interval, CI): 5:04 (1.47 to 17.28), p = 0.018]. However, this association did not survive some correction bit testing. No other significant associations between PAI-1 tag SNPs and haplotypes revealed. In addition, no significant effect of the mutation load of PAI-1 tag SNPs on the risk of developing type 2 diabetes found in the course DR.