Selective inhibition of brain endothelial Rho-kinase-2 provides optimal protection of an in vitro blood-brain barrier from tissue-type plasminogen activator and plasmin.

Rho-kinase (ROCK) inhibition, widely used in cardiovascular disease, could protect the blood-brain barrier (BBB) ​​from damage during thrombolysis rt-PA-induced. While the use of inhibitors of ROCK nonselective as fasudil together with rt-PA can be deterred by the possibility of hypotension side effects and inadequate capacity to block the activity of rt-PA detrimental to endothelial cells of the brain (BEC), a selective ROCK-2 inhibition may overcome these limitations , Here, we examine ROCK-2 expression in primary brain cells and compare the ability of fasudil and KD 025, a selective ROCK-2 inhibitor, to attenuate the rt-PA-induced BBB disruption in vitro human models.

ROCK-2 highly expressed relative to ROCK-1 in all kinds of human and mouse brain cells and particularly enriched in rat brain endothelial cells and astrocytes compared to neurons. KD 025 is stronger than fasudil in attenuation of rt-PA-induced plasminogen-and permeation BBB under normoxia, but especially under conditions such as stroke. Importantly, only KD 025, but not fasudil, was able to block the increase in the permeability of rt-PA-dependent, changes in morphology and tight junction degradation in BECs isolated.

Selective inhibition of ROCK-2 further diminished rt-PA-induced phosphorylation of myosin, transformation and activation of matrix metalloprotease in astrocytes. These findings highlight the isoforms ROCK-2 as the main driving BBB endothelial disorders and brain damage by rt-PA and the potential of KD 025 to optimally protect the BBB during thrombolysis.

Evaluation fibrinolytic Inhibitors : alpha- two -Antiplasmin and Plasminogen Activator inhibitors 1 patients with Obstructive Sleep Apnea.

Obstructive sleep apnea (OSA) inducing thrombophilia and reduced fibrinolysis. Alpha-2-antiplasmin (a-2-AP) and plasminogen activator inhibitor 1 (PAI-1) is the main inhibitor of the fibrinolytic system. Increasing concentrations of this factor is associated with a higher risk of cardiovascular disease. The purpose of this study was to evaluate plasma-2-AP and PAI-1 in patients with OSA and evaluate the correlation with polysomnographic records and selected risk factors of cardiovascular disease.

The study group comprised 45 patients with OSA, and the control group consisted of 19 patients who did not meet the diagnostic criteria of OSA. Plasma-2-AP and PAI-1 concentrations assessed by enzyme-linked immunosorbent assay (ELISA). In the study group, the median value of plasma-2-AP is higher than the control group (11.89 vs 157.34 pg / ml, respectively, P <0.0001). A-2-AP concentration increases proportionally with the severity of OSA.

The concentration of 2-AP positively correlated with the index of apnea-hypopnoea (AHI), apnea index (AI), respiratory disturbance time (RDT), and the index desaturaion (DI), and negatively correlated with oxygen saturation, mean and minimum (SpO2 means, SpO2 min, respectively). The median value of PAI-1 was higher in the study group than the control group (12.55 vs. 5.40 ng / ml, respectively, P = 0.006) and increased with the severity of OSA. PAI-1 concentrations correlated positively with AHI, AI, RDT, DI, and body mass index (BMI) and negatively correlated with mean SpO2 and SpO2 min.

Higher plasma concentrations of 2-AP and PAI-1 in patients with OSA showed that these patients had increased prothrombotic activity. OSA increases the risk of cardiovascular complications such as increased prothrombotic activity.

Recombinant Mouse Plasminogen Activator Inhibitor-2
MBS146819-1mg	MyBiosource	1mg	EUR 5345

Recombinant Mouse Plasminogen Activator Inhibitor-2
MBS146819-5x1mg	MyBiosource	5x1mg	EUR 23725

Plasminogen Activator Inhibitor-2 Mouse Recombinant
rAP-1489	Angio Proteomie	Inquiry	Ask for price

Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 320

Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 320

Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 520

Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 515

Recombinant Mouse Plasminogen activator inhibitor 1
MBS963855-05mgYeast	MyBiosource	0.5mg(Yeast)	EUR 1260

Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-002mg	MyBiosource	0.02mg	EUR 380

Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-01mg	MyBiosource	0.1mg	EUR 650

Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-1mg	MyBiosource	1mg	EUR 2525

Recombinant mouse Plasminogen activator inhibitor 1
MBS9420661-5x1mg	MyBiosource	5x1mg	EUR 11205

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
CSB-EP021081MO	Cusabio	2166 mg	Ask for price

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
CSB-EP021081MO-20ug	Cusabio	20ug	Ask for price
Description: 23-402aa

Recombinant Mouse Plasminogen activator inhibitor 1(Serpine1)
AP70764	SAB	1mg	EUR 2826

Recombinant Mouse Plasminogen activator inhibitor 1(Serpine1)
AP72777	SAB	each	Ask for price

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
CSB-YP021081MO	Cusabio	5989 mg	Ask for price

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
CSB-YP021081MO-20ug	Cusabio	20ug	Ask for price
Description: 23-402aa

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC21989-100ug	Biomatik Corporation	100ug	EUR 705.1

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC21989-1mg	Biomatik Corporation	1mg	EUR 3237

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC21989-20ug	Biomatik Corporation	20ug	EUR 353.4

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC24943-100ug	Biomatik Corporation	100ug	EUR 702.9

Recombinant Mouse Plasminogen activator inhibitor 1 (Serpine1)
RPC24943-20ug	Biomatik Corporation	20ug	EUR 353.4

Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-002mgBaculovirus	MyBiosource	0.02mg(Baculovirus)	EUR 1285

Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 965

Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 1080

Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 1125

Recombinant Mouse Plasminogen activator inhibitor 2, macrophage (Serpinb2)
MBS962179-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 1230

Recombinant Human Plasminogen Activator Inhibitor-2
AP60417	SAB	100ug	EUR 1554

Recombinant Human Plasminogen Activator Inhibitor-2
P1567-.01	ApexBio	10ug	EUR 272.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Human Plasminogen Activator Inhibitor-2
P1567-.1	ApexBio	100ug	EUR 1560.8
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Human Plasminogen Activator Inhibitor-2
P1567-.5	ApexBio	500ug	EUR 3503.2
Description: Peptides & Proteins|Recombinant Proteins

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-001mg	MyBiosource	0.01mg	EUR 170

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-005mg	MyBiosource	0.05mg	EUR 295

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-01mg	MyBiosource	0.1mg	EUR 450

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-02mg	MyBiosource	0.2mg	EUR 545

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018222-05mg	MyBiosource	0.5mg	EUR 1040

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-001mg	MyBiosource	0.01mg	EUR 180

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-005mg	MyBiosource	0.05mg	EUR 330

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-01mg	MyBiosource	0.1mg	EUR 500

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-02mg	MyBiosource	0.2mg	EUR 615

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018365-05mg	MyBiosource	0.5mg	EUR 1170

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-001mg	MyBiosource	0.01mg	EUR 175

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-005mg	MyBiosource	0.05mg	EUR 315

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-01mg	MyBiosource	0.1mg	EUR 475

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-02mg	MyBiosource	0.2mg	EUR 580

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
MBS2018456-05mg	MyBiosource	0.5mg	EUR 1100

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU56751-100ug	Biomatik Corporation	100ug	EUR 470.4

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU56751-1mg	Biomatik Corporation	1mg	EUR 2184

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU56751-50ug	Biomatik Corporation	50ug	EUR 385

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43313-100ug	Biomatik Corporation	100ug	EUR 524.7

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43313-1mg	Biomatik Corporation	1mg	EUR 2325.7

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43313-50ug	Biomatik Corporation	50ug	EUR 421.3

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43314-100ug	Biomatik Corporation	100ug	EUR 562.1

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43314-1mg	Biomatik Corporation	1mg	EUR 2489.5

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43314-50ug	Biomatik Corporation	50ug	EUR 451

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43315-100ug	Biomatik Corporation	100ug	EUR 599.5

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43315-1mg	Biomatik Corporation	1mg	EUR 2653.3

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPU43315-50ug	Biomatik Corporation	50ug	EUR 480.7

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPA531Hu01	Cloud-Clone	10ug	EUR 170

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
4-RPA531Hu01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Human Plasminogen Activator Inhibitor 2 expressed in: E.coli

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPA531Mu01	Cloud-Clone	10ug	EUR 182

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
4-RPA531Mu01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Mouse Plasminogen Activator Inhibitor 2 expressed in: E.coli

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
RPA531Ra01	Cloud-Clone	10ug	EUR 194

Recombinant Plasminogen Activator Inhibitor 2 (PAI2)
4-RPA531Ra01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Rat Plasminogen Activator Inhibitor 2 expressed in: E.coli

Recombinant human Plasminogen activator inhibitor 2
P1738	FN Test	100ug	Ask for price
Description: Recombinant protein for human Plasminogen activator inhibitor 2

Plasminogen Activator Inhibitor-1 (Recombinant)
20-abx073514	Abbexa	Ask for price Ask for price Ask for price	5 ug 25 ug 1 mg

Plasminogen Activator Inhibitor Type 1, Recombinant, Mouse (PAI-1)
MBS636215-05mg	MyBiosource	0.5mg	EUR 1895

Plasminogen Activator Inhibitor Type 1, Recombinant, Mouse (PAI-1)
MBS636215-5x05mg	MyBiosource	5x0.5mg	EUR 8310

Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 320

Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 520

Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-1mgEColi	MyBiosource	1mg(E-Coli)	EUR 1925

Recombinant Rat Plasminogen activator inhibitor 1
MBS1189391-5x1mgEColi	MyBiosource	5x1mg(E-Coli)	EUR 8405

Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-002mg	MyBiosource	0.02mg	EUR 380

Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-01mg	MyBiosource	0.1mg	EUR 650

Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-1mg	MyBiosource	1mg	EUR 2525

Recombinant Rat Plasminogen activator inhibitor 1
MBS9420662-5x1mg	MyBiosource	5x1mg	EUR 11205

Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-0005mg	MyBiosource	0.005mg	EUR 240

Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-0025mg	MyBiosource	0.025mg	EUR 310

Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-1mg	MyBiosource	1mg	EUR 3165

Recombinant Human Plasminogen Activator Inhibitor-1
MBS143203-5x1mg	MyBiosource	5x1mg	EUR 13925

Plasminogen Activator Inhibitor-1 Human Recombinant
rAP-4753	Angio Proteomie	Inquiry	Ask for price

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-001mg	MyBiosource	0.01mg	EUR 160

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-005mg	MyBiosource	0.05mg	EUR 280

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-01mg	MyBiosource	0.1mg	EUR 405

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-02mg	MyBiosource	0.2mg	EUR 490

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2010253-05mg	MyBiosource	0.5mg	EUR 930

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-001mg	MyBiosource	0.01mg	EUR 160

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-005mg	MyBiosource	0.05mg	EUR 280

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-01mg	MyBiosource	0.1mg	EUR 405

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-02mg	MyBiosource	0.2mg	EUR 490

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2105272-05mg	MyBiosource	0.5mg	EUR 930

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-001mg	MyBiosource	0.01mg	EUR 165

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-005mg	MyBiosource	0.05mg	EUR 285

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-01mg	MyBiosource	0.1mg	EUR 425

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-02mg	MyBiosource	0.2mg	EUR 515

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2030669-05mg	MyBiosource	0.5mg	EUR 980

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-001mg	MyBiosource	0.01mg	EUR 170

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-005mg	MyBiosource	0.05mg	EUR 305

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-01mg	MyBiosource	0.1mg	EUR 460

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-02mg	MyBiosource	0.2mg	EUR 560

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
MBS2029177-05mg	MyBiosource	0.5mg	EUR 1065

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU55545-100ug	Biomatik Corporation	100ug	EUR 601.7

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU55545-1mg	Biomatik Corporation	1mg	EUR 2371.2

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU55545-50ug	Biomatik Corporation	50ug	EUR 364.8

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU56752-100ug	Biomatik Corporation	100ug	EUR 470.4

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU56752-1mg	Biomatik Corporation	1mg	EUR 2184

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU56752-50ug	Biomatik Corporation	50ug	EUR 385

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU51492-100ug	Biomatik Corporation	100ug	EUR 492.8

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU51492-1mg	Biomatik Corporation	1mg	EUR 2184

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU51492-50ug	Biomatik Corporation	50ug	EUR 396

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU43312-100ug	Biomatik Corporation	100ug	EUR 468.6

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU43312-1mg	Biomatik Corporation	1mg	EUR 2074.8

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU43312-50ug	Biomatik Corporation	50ug	EUR 376.2

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU52990-100ug	Biomatik Corporation	100ug	EUR 542.3

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU52990-1mg	Biomatik Corporation	1mg	EUR 2402.4

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPU52990-50ug	Biomatik Corporation	50ug	EUR 435.6

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Hu01	Cloud-Clone	10ug	EUR 152

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Hu01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Human Plasminogen Activator Inhibitor 1 expressed in: E.coli

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Hu02	Cloud-Clone	10ug	EUR 152

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Hu02	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Human Plasminogen Activator Inhibitor 1 expressed in: E.coli

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Mu01	Cloud-Clone	10ug	EUR 160

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Mu01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Mouse Plasminogen Activator Inhibitor 1 expressed in: E.coli

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Ra01	Cloud-Clone	10ug	EUR 176

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
4-RPA532Ra01	Cloud-Clone	Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price Ask for price	10ug 50ug 100 ug 200 ug 500 ug 1 mg 5 mg
Description: Recombinant Rat Plasminogen Activator Inhibitor 1 expressed in: E.coli

Recombinant Plasminogen Activator Inhibitor 1 (PAI1)
RPA532Si01	Cloud-Clone	10ug	EUR 164

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
CSB-MP021070HU	Cusabio	4968 mg	Ask for price

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
CSB-MP021070HU-20ug	Cusabio	20ug	Ask for price
Description: 1-415aa

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
CSB-YP021070HU	Cusabio	5987 mg	Ask for price

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
CSB-YP021070HU-20ug	Cusabio	20ug	Ask for price
Description: 1-415aa

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-002mgMammalianCell	MyBiosource	0.02mg(Mammalian-Cell)	EUR 425

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 320

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-01mgMammalianCell	MyBiosource	0.1mg(Mammalian-Cell)	EUR 1015

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 515

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
MBS965342-05mgYeast	MyBiosource	0.5mg(Yeast)	EUR 1260

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
RPC26411-100ug	Biomatik Corporation	100ug	EUR 1218.8

Recombinant Human Plasminogen activator inhibitor 2 (SERPINB2)
RPC26411-20ug	Biomatik Corporation	20ug	EUR 484

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 320

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-002mgYeast	MyBiosource	0.02mg(Yeast)	EUR 320

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 520

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-01mgYeast	MyBiosource	0.1mg(Yeast)	EUR 515

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS951741-05mgYeast	MyBiosource	0.5mg(Yeast)	EUR 1260

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-002mg	MyBiosource	0.02mg	EUR 380

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-01mg	MyBiosource	0.1mg	EUR 650

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-1mg	MyBiosource	1mg	EUR 2525

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9420660-5x1mg	MyBiosource	5x1mg	EUR 11205

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-002mg	MyBiosource	0.02mg	EUR 380

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-01mg	MyBiosource	0.1mg	EUR 650

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-05mg	MyBiosource	0.5mg	EUR 1655

Recombinant Rat Plasminogen activator inhibitor 2 type A
MBS9422489-5x05mg	MyBiosource	5x0.5mg	EUR 7290

Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-002mgEColi	MyBiosource	0.02mg(E-Coli)	EUR 255

Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-01mgEColi	MyBiosource	0.1mg(E-Coli)	EUR 405

Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-1mgEColi	MyBiosource	1mg(E-Coli)	EUR 1425

Recombinant Human Plasminogen activator inhibitor 1
MBS1265498-5x1mgEColi	MyBiosource	5x1mg(E-Coli)	EUR 6215

Recombinant human Plasminogen activator inhibitor 1
MBS961954-005mg	MyBiosource	0.05mg	EUR 260

Recombinant human Plasminogen activator inhibitor 1
MBS961954-02mg	MyBiosource	0.2mg	EUR 560

Recombinant human Plasminogen activator inhibitor 1
MBS961954-05mg	MyBiosource	0.5mg	EUR 875

Recombinant human Plasminogen activator inhibitor 1
MBS961954-1mg	MyBiosource	1mg	EUR 1325

Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-002mg	MyBiosource	0.02mg	EUR 285

Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-01mg	MyBiosource	0.1mg	EUR 470

Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-1mg	MyBiosource	1mg	EUR 1785

Recombinant Human Plasminogen activator inhibitor 1
MBS9421915-5x1mg	MyBiosource	5x1mg	EUR 7885

Mouse Plasminogen Activator Inhibitor 2 ELISA kit
E01A24356	BlueGene	96T	EUR 700
Description: ELISA

Mouse Plasminogen Activator Inhibitor 2 ELISA kit
E03P0057-192T	BlueGene	192 tests	EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Plasminogen Activator Inhibitor 2 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

A significant effect of rs2070682 in the risk of early onset DR found in codominant model of inheritance [odds ratio, OR (95% confidence interval, CI): 5:04 (1.47 to 17.28), p = 0.018]. However, this association did not survive some correction bit testing. No other significant associations between PAI-1 tag SNPs and haplotypes revealed. In addition, no significant effect of the mutation load of PAI-1 tag SNPs on the risk of developing type 2 diabetes found in the course DR.