Deficiency of Plasminogen Activator Inhibitor Type 2 Limits Brain Edema Formation after Traumatic Brain Injury.

Plasminogen activator inhibitor-2 (PAI-2 / SerpinB2) inhibits extracellular urokinase plasminogen activator (uPA). In physiological conditions, PAI-2 is expressed at low levels but quickly due to triggers inflammation. This is a negative regulator of fibrinolysis and serves to stabilize the clot. In this study, PAI-2 expression upregulated 25 fold in the brain tissues pericontusional at 6 hours after traumatic brain injury (TBI), with a maximum increase 87-fold at 12 h.

To investigate the potential adverse effects of PAI-2 in the process of post-traumatic secondary, man-deficiency PAI-2 (PAI-2 KO) and wild-type mice (WT) were subjected to TBI by controlled cortical impact injury. The volume of brain lesions, and inflammation of the brain is no different. Total brain volume was significantly smaller in the PAI-2 KO, showed reduced brain swelling. The water content of the brain at 24 hours post-insult was significantly smaller in the PAI-2 knockout mice.

Marker vasogenic cerebral edema showed no difference in the blood-brain barrier integrity and protein expression of blood-brain barrier (claudin-5, zonula occludens-1). Unlike the plasminogen activator inhibitor-1 (PAI-1), PAI-2 plays a limited role for the formation of brain lesions and do not affect the integrity of the blood-brain barrier. PAI-2 contributes to the formation of brain edema and because it could be a promising new targets for treating post-traumatic brain edema.

Deficiency of <em>Plasminogen</em> <em>Activator</em> <em>Inhibitor</em> Type <em>2</em> Limits Brain Edema Formation after Traumatic Brain Injury.
Deficiency of Plasminogen Activator Inhibitor Type 2 Limits Brain Edema Formation after Traumatic Brain Injury.

Plasminogen driving inhibitors two (PAI two ) on the potential of invasive cell hepatocellular carcinoma in vitro through uPA- and RB / E two F1-related mechanisms.

Plasminogen activator inhibitor 2 (PAI2) has been shown to be associated with invasive phenotype and prognosis in hepatocellular carcinoma (HCC). However, the biological role and mechanisms underlying the invasion of HCC has not been explored. This study aims to address issues.First, sub-lines in the PAI2 was stably expressed and silence established by MHCC97H and BEL7402 cell lines, respectively.

Wound healing and transwell test were applied to evaluate cell migration and invasion. Urokinase-type plasminogen activator (uPA) activity was measured using ELISA kit. Real-time RT-PCR and western blotting were used to demonstrate gene expression at the mRNA and protein level. E2F1 expression in human specimens is determined by tissue microarray-based immunohistochemical staining.The sub-lines, MHCC97H-PAI2 and BEL7402-siPAI2, successfully established.

The second sub-lines do far lower and higher strength migration and invasion, respectively, in contrast to controls. In MHCC97H-PAI2 sub-line, intra-medium uPA activity significantly decreased, while the expression of RB clearly increased, compared to the control. The BEL7402-siPAI2 sub-line is presented the opposite trend. To identify the role of RB / E2F1 pathway, we transient expressed E2F1 in MHCC97H-PAI2 sub-line, and largely reversed the inhibitory effect PAI2 on cell migration and invasion, through the set several matrix metalloproteinase and epithelial-mesenchymal transition.

In HCC specimens, E2F1 expression was much higher in the tumor than in non-tumor tissue, and significantly correlated with Edmondson-Steiner grade, overall as well as data survival.Our free tumor showed that invasive potential PAI2 inhibit HCC cells through uPA – and RB / E2F1-related mechanisms.

Phospho-ELK1 (Ser383) Antibody

CSB-PA962606-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-ELK1 (Ser383). Recognizes Phospho-ELK1 (Ser383) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

ZNF596 Antibody

CSB-PA962806-
EUR 335
Description: A polyclonal antibody against ZNF596. Recognizes ZNF596 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

ZNF596 Antibody

CSB-PA962806-100ul 100ul
EUR 316
Description: A polyclonal antibody against ZNF596. Recognizes ZNF596 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

CA14 Antibody

CSB-PA962891-
EUR 335
Description: A polyclonal antibody against CA14. Recognizes CA14 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CA14 Antibody

CSB-PA962891-100ul 100ul
EUR 316
Description: A polyclonal antibody against CA14. Recognizes CA14 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

SF1 (Ab-82) Antibody

CSB-PA963117-
EUR 335
Description: A polyclonal antibody against SF1 (Ab-82). Recognizes SF1 (Ab-82) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

SF1 (Ab-82) Antibody

CSB-PA963117-100ul 100ul
EUR 316
Description: A polyclonal antibody against SF1 (Ab-82). Recognizes SF1 (Ab-82) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

CCT7 Antibody

CSB-PA963179-
EUR 335
Description: A polyclonal antibody against CCT7. Recognizes CCT7 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CCT7 Antibody

CSB-PA963179-100ul 100ul
EUR 316
Description: A polyclonal antibody against CCT7. Recognizes CCT7 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

Phospho-MAPT (Ser404) Antibody

CSB-PA963344-
EUR 335
Description: A polyclonal antibody against Phospho-MAPT (Ser404). Recognizes Phospho-MAPT (Ser404) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-MAPT (Ser404) Antibody

CSB-PA963344-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-MAPT (Ser404). Recognizes Phospho-MAPT (Ser404) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

CST1 Antibody

CSB-PA963535-
EUR 335
Description: A polyclonal antibody against CST1. Recognizes CST1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:500

CST1 Antibody

CSB-PA963535-100ul 100ul
EUR 316
Description: A polyclonal antibody against CST1. Recognizes CST1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC, IF;IHC:1:50-1:100, IF:1:100-1:500

Phospho-CCND1 (Ser90) Antibody

CSB-PA963558-
EUR 335
Description: A polyclonal antibody against Phospho-CCND1 (Ser90). Recognizes Phospho-CCND1 (Ser90) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-CCND1 (Ser90) Antibody

CSB-PA963558-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-CCND1 (Ser90). Recognizes Phospho-CCND1 (Ser90) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Histone H3K27me3 Antibody

CSB-PA963638-
EUR 335
Description: A polyclonal antibody against Histone H3K27me3. Recognizes Histone H3K27me3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, IP, ChIP;WB:1:500-1:2000, IHC:1:50-1:200, IF:1:50-1:200, IP:1:50-1:200, ChIP:1:50-1:200

Histone H3K27me3 Antibody

CSB-PA963638-100ul 100ul
EUR 380
Description: A polyclonal antibody against Histone H3K27me3. Recognizes Histone H3K27me3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF, IP, ChIP;WB:1:500-1:2000, IHC:1:50-1:200, IF:1:50-1:200, IP:1:50-1:200, ChIP:1:50-1:200

MYOM1 Antibody

CSB-PA964006-
EUR 335
Description: A polyclonal antibody against MYOM1. Recognizes MYOM1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

MYOM1 Antibody

CSB-PA964006-100ul 100ul
EUR 316
Description: A polyclonal antibody against MYOM1. Recognizes MYOM1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

ADD3 Antibody

CSB-PA964364-
EUR 335
Description: A polyclonal antibody against ADD3. Recognizes ADD3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ADD3 Antibody

CSB-PA964364-100ul 100ul
EUR 316
Description: A polyclonal antibody against ADD3. Recognizes ADD3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

TP53 (Ab-315) Antibody

CSB-PA964395-
EUR 335
Description: A polyclonal antibody against TP53 (Ab-315). Recognizes TP53 (Ab-315) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

TP53 (Ab-315) Antibody

CSB-PA964395-100ul 100ul
EUR 316
Description: A polyclonal antibody against TP53 (Ab-315). Recognizes TP53 (Ab-315) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

PRLR Antibody

CSB-PA964526-
EUR 335
Description: A polyclonal antibody against PRLR. Recognizes PRLR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

PRLR Antibody

CSB-PA964526-100ul 100ul
EUR 316
Description: A polyclonal antibody against PRLR. Recognizes PRLR from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

PPP2R3C Antibody

CSB-PA964594-
EUR 335
Description: A polyclonal antibody against PPP2R3C. Recognizes PPP2R3C from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PPP2R3C Antibody

CSB-PA964594-100ul 100ul
EUR 316
Description: A polyclonal antibody against PPP2R3C. Recognizes PPP2R3C from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

BAGE2 Antibody

CSB-PA964722-
EUR 335
Description: A polyclonal antibody against BAGE2. Recognizes BAGE2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

BAGE2 Antibody

CSB-PA964722-100ul 100ul
EUR 316
Description: A polyclonal antibody against BAGE2. Recognizes BAGE2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

PIK3R1/PIK3R3 (Ab-467/199) Antibody

CSB-PA965833-
EUR 335
Description: A polyclonal antibody against PIK3R1/PIK3R3 (Ab-467/199). Recognizes PIK3R1/PIK3R3 (Ab-467/199) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

PIK3R1/PIK3R3 (Ab-467/199) Antibody

CSB-PA965833-100ul 100ul
EUR 316
Description: A polyclonal antibody against PIK3R1/PIK3R3 (Ab-467/199). Recognizes PIK3R1/PIK3R3 (Ab-467/199) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

MAP2K1 (Ab-291) Antibody

CSB-PA965933-
EUR 335
Description: A polyclonal antibody against MAP2K1 (Ab-291). Recognizes MAP2K1 (Ab-291) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

MAP2K1 (Ab-291) Antibody

CSB-PA965933-100ul 100ul
EUR 316
Description: A polyclonal antibody against MAP2K1 (Ab-291). Recognizes MAP2K1 (Ab-291) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:200

Phospho-HSF1 (Ser307) Antibody

CSB-PA966483-
EUR 335
Description: A polyclonal antibody against Phospho-HSF1 (Ser307). Recognizes Phospho-HSF1 (Ser307) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

Phospho-HSF1 (Ser307) Antibody

CSB-PA966483-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-HSF1 (Ser307). Recognizes Phospho-HSF1 (Ser307) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

ASCL2 Antibody

CSB-PA966616-
EUR 335
Description: A polyclonal antibody against ASCL2. Recognizes ASCL2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ASCL2 Antibody

CSB-PA966616-100ul 100ul
EUR 316
Description: A polyclonal antibody against ASCL2. Recognizes ASCL2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

HNRNPC Antibody

CSB-PA966696-
EUR 335
Description: A polyclonal antibody against HNRNPC. Recognizes HNRNPC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

HNRNPC Antibody

CSB-PA966696-100ul 100ul
EUR 316
Description: A polyclonal antibody against HNRNPC. Recognizes HNRNPC from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

GZMH Antibody

CSB-PA966723-
EUR 335
Description: A polyclonal antibody against GZMH. Recognizes GZMH from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

GZMH Antibody

CSB-PA966723-100ul 100ul
EUR 316
Description: A polyclonal antibody against GZMH. Recognizes GZMH from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

Phospho-SYT1 (Ser309) Antibody

CSB-PA967008-
EUR 335
Description: A polyclonal antibody against Phospho-SYT1 (Ser309). Recognizes Phospho-SYT1 (Ser309) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:200

Phospho-SYT1 (Ser309) Antibody

CSB-PA967008-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-SYT1 (Ser309). Recognizes Phospho-SYT1 (Ser309) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:200

NRSN1 Antibody

CSB-PA967502-
EUR 335
Description: A polyclonal antibody against NRSN1. Recognizes NRSN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

NRSN1 Antibody

CSB-PA967502-100ul 100ul
EUR 316
Description: A polyclonal antibody against NRSN1. Recognizes NRSN1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

RABL2A Antibody

CSB-PA967554-
EUR 335
Description: A polyclonal antibody against RABL2A. Recognizes RABL2A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

RABL2A Antibody

CSB-PA967554-100ul 100ul
EUR 316
Description: A polyclonal antibody against RABL2A. Recognizes RABL2A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

HDAC3 Antibody

CSB-PA967736-
EUR 335
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

HDAC3 Antibody

CSB-PA967736-100ul 100ul
EUR 316
Description: A polyclonal antibody against HDAC3. Recognizes HDAC3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

AKR1A1 Antibody

CSB-PA967994-
EUR 335
Description: A polyclonal antibody against AKR1A1. Recognizes AKR1A1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AKR1A1 Antibody

CSB-PA967994-100ul 100ul
EUR 316
Description: A polyclonal antibody against AKR1A1. Recognizes AKR1A1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CLCN4 Antibody

CSB-PA968321-
EUR 335
Description: A polyclonal antibody against CLCN4. Recognizes CLCN4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200

CLCN4 Antibody

CSB-PA968321-100ul 100ul
EUR 316
Description: A polyclonal antibody against CLCN4. Recognizes CLCN4 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:3000, IHC:1:50-1:200, IF:1:100-1:200

ATF1 Antibody

CSB-PA968509-
EUR 335
Description: A polyclonal antibody against ATF1. Recognizes ATF1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

ATF1 Antibody

CSB-PA968509-100ul 100ul
EUR 316
Description: A polyclonal antibody against ATF1. Recognizes ATF1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

Phospho-MEF2A (Ser408) Antibody

CSB-PA968646-
EUR 335
Description: A polyclonal antibody against Phospho-MEF2A (Ser408). Recognizes Phospho-MEF2A (Ser408) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

Phospho-MEF2A (Ser408) Antibody

CSB-PA968646-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-MEF2A (Ser408). Recognizes Phospho-MEF2A (Ser408) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

WISP2 Antibody

CSB-PA968927-
EUR 335
Description: A polyclonal antibody against WISP2. Recognizes WISP2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

WISP2 Antibody

CSB-PA968927-100ul 100ul
EUR 316
Description: A polyclonal antibody against WISP2. Recognizes WISP2 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-GRIN2B (Tyr1474) Antibody

CSB-PA969425-
EUR 335
Description: A polyclonal antibody against Phospho-GRIN2B (Tyr1474). Recognizes Phospho-GRIN2B (Tyr1474) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

Phospho-GRIN2B (Tyr1474) Antibody

CSB-PA969425-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-GRIN2B (Tyr1474). Recognizes Phospho-GRIN2B (Tyr1474) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:1000, IF:1:100-1:200

PMAIP1 Antibody

CSB-PA969433-
EUR 335
Description: A polyclonal antibody against PMAIP1. Recognizes PMAIP1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

PMAIP1 Antibody

CSB-PA969433-100ul 100ul
EUR 316
Description: A polyclonal antibody against PMAIP1. Recognizes PMAIP1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

Phospho-ZAP70 (Tyr319) Antibody

CSB-PA969675-
EUR 335
Description: A polyclonal antibody against Phospho-ZAP70 (Tyr319). Recognizes Phospho-ZAP70 (Tyr319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-ZAP70 (Tyr319) Antibody

CSB-PA969675-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-ZAP70 (Tyr319). Recognizes Phospho-ZAP70 (Tyr319) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

RPS4X Antibody

CSB-PA969688-
EUR 335
Description: A polyclonal antibody against RPS4X. Recognizes RPS4X from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

RPS4X Antibody

CSB-PA969688-100ul 100ul
EUR 316
Description: A polyclonal antibody against RPS4X. Recognizes RPS4X from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IF;WB:1:500-1:3000, IF:1:100-1:500

TUBB3 Antibody

CSB-PA969690-
EUR 335
Description: A polyclonal antibody against TUBB3. Recognizes TUBB3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

TUBB3 Antibody

CSB-PA969690-100ul 100ul
EUR 316
Description: A polyclonal antibody against TUBB3. Recognizes TUBB3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

NT5C1B Antibody

CSB-PA969848-
EUR 335
Description: A polyclonal antibody against NT5C1B. Recognizes NT5C1B from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500

NT5C1B Antibody

CSB-PA969848-100ul 100ul
EUR 316
Description: A polyclonal antibody against NT5C1B. Recognizes NT5C1B from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500

AKT1 (Ab-450) Antibody

CSB-PA969941-
EUR 335
Description: A polyclonal antibody against AKT1 (Ab-450). Recognizes AKT1 (Ab-450) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

AKT1 (Ab-450) Antibody

CSB-PA969941-100ul 100ul
EUR 316
Description: A polyclonal antibody against AKT1 (Ab-450). Recognizes AKT1 (Ab-450) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Phospho-MAP2K4 (Ser80) Antibody

CSB-PA970074-
EUR 335
Description: A polyclonal antibody against Phospho-MAP2K4 (Ser80). Recognizes Phospho-MAP2K4 (Ser80) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

Phospho-MAP2K4 (Ser80) Antibody

CSB-PA970074-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-MAP2K4 (Ser80). Recognizes Phospho-MAP2K4 (Ser80) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:100, IF:1:100-1:200

RAB29 Antibody

CSB-PA970360-
EUR 335
Description: A polyclonal antibody against RAB29. Recognizes RAB29 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

RAB29 Antibody

CSB-PA970360-100ul 100ul
EUR 316
Description: A polyclonal antibody against RAB29. Recognizes RAB29 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

KIR2DL5B Antibody

CSB-PA970470-
EUR 335
Description: A polyclonal antibody against KIR2DL5B. Recognizes KIR2DL5B from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500

KIR2DL5B Antibody

CSB-PA970470-100ul 100ul
EUR 316
Description: A polyclonal antibody against KIR2DL5B. Recognizes KIR2DL5B from Human. This antibody is Unconjugated. Tested in the following application: ELISA, IF;IF:1:100-1:500

IKZF3 Antibody

CSB-PA970658-
EUR 335
Description: A polyclonal antibody against IKZF3. Recognizes IKZF3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

IKZF3 Antibody

CSB-PA970658-100ul 100ul
EUR 316
Description: A polyclonal antibody against IKZF3. Recognizes IKZF3 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

USP13 Antibody

CSB-PA970742-
EUR 335
Description: A polyclonal antibody against USP13. Recognizes USP13 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

USP13 Antibody

CSB-PA970742-100ul 100ul
EUR 316
Description: A polyclonal antibody against USP13. Recognizes USP13 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

ABCD4 Antibody

CSB-PA970746-
EUR 335
Description: A polyclonal antibody against ABCD4. Recognizes ABCD4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ABCD4 Antibody

CSB-PA970746-100ul 100ul
EUR 316
Description: A polyclonal antibody against ABCD4. Recognizes ABCD4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AATF Antibody

CSB-PA970851-
EUR 335
Description: A polyclonal antibody against AATF. Recognizes AATF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AATF Antibody

CSB-PA970851-100ul 100ul
EUR 316
Description: A polyclonal antibody against AATF. Recognizes AATF from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

MOB1B Antibody

CSB-PA970943-
EUR 335
Description: A polyclonal antibody against MOB1B. Recognizes MOB1B from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

MOB1B Antibody

CSB-PA970943-100ul 100ul
EUR 316
Description: A polyclonal antibody against MOB1B. Recognizes MOB1B from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PLG Antibody

CSB-PA970985-
EUR 335
Description: A polyclonal antibody against PLG. Recognizes PLG from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PLG Antibody

CSB-PA970985-100ul 100ul
EUR 316
Description: A polyclonal antibody against PLG. Recognizes PLG from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

OXR1 Antibody

CSB-PA971107-
EUR 335
Description: A polyclonal antibody against OXR1. Recognizes OXR1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

OXR1 Antibody

CSB-PA971107-100ul 100ul
EUR 316
Description: A polyclonal antibody against OXR1. Recognizes OXR1 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

NBPF5P Antibody

CSB-PA971232-
EUR 335
Description: A polyclonal antibody against NBPF5P. Recognizes NBPF5P from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

NBPF5P Antibody

CSB-PA971232-100ul 100ul
EUR 316
Description: A polyclonal antibody against NBPF5P. Recognizes NBPF5P from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

KCNJ4 Antibody

CSB-PA971432-
EUR 335
Description: A polyclonal antibody against KCNJ4. Recognizes KCNJ4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

KCNJ4 Antibody

CSB-PA971432-100ul 100ul
EUR 316
Description: A polyclonal antibody against KCNJ4. Recognizes KCNJ4 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CBX5 (Ab-92) Antibody

CSB-PA971900-
EUR 335
Description: A polyclonal antibody against CBX5 (Ab-92). Recognizes CBX5 (Ab-92) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

CBX5 (Ab-92) Antibody

CSB-PA971900-100ul 100ul
EUR 316
Description: A polyclonal antibody against CBX5 (Ab-92). Recognizes CBX5 (Ab-92) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

Phospho-BCL2 (Ser87) Antibody

CSB-PA971921-
EUR 335
Description: A polyclonal antibody against Phospho-BCL2 (Ser87). Recognizes Phospho-BCL2 (Ser87) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-BCL2 (Ser87) Antibody

CSB-PA971921-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-BCL2 (Ser87). Recognizes Phospho-BCL2 (Ser87) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

CHFR Antibody

CSB-PA972040-
EUR 335
Description: A polyclonal antibody against CHFR. Recognizes CHFR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CHFR Antibody

CSB-PA972040-100ul 100ul
EUR 316
Description: A polyclonal antibody against CHFR. Recognizes CHFR from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AQP12A Antibody

CSB-PA972136-
EUR 335
Description: A polyclonal antibody against AQP12A. Recognizes AQP12A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

AQP12A Antibody

CSB-PA972136-100ul 100ul
EUR 316
Description: A polyclonal antibody against AQP12A. Recognizes AQP12A from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

Phospho-FANCG (Ser383) Antibody

CSB-PA972302-
EUR 335
Description: A polyclonal antibody against Phospho-FANCG (Ser383). Recognizes Phospho-FANCG (Ser383) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

Phospho-FANCG (Ser383) Antibody

CSB-PA972302-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-FANCG (Ser383). Recognizes Phospho-FANCG (Ser383) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PRIM1 Antibody

CSB-PA972371-
EUR 335
Description: A polyclonal antibody against PRIM1. Recognizes PRIM1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PRIM1 Antibody

CSB-PA972371-100ul 100ul
EUR 316
Description: A polyclonal antibody against PRIM1. Recognizes PRIM1 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ASH2L Antibody

CSB-PA972879-
EUR 335
Description: A polyclonal antibody against ASH2L. Recognizes ASH2L from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

ASH2L Antibody

CSB-PA972879-100ul 100ul
EUR 316
Description: A polyclonal antibody against ASH2L. Recognizes ASH2L from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

ADCK3 Antibody

CSB-PA973086-
EUR 335
Description: A polyclonal antibody against ADCK3. Recognizes ADCK3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ADCK3 Antibody

CSB-PA973086-100ul 100ul
EUR 316
Description: A polyclonal antibody against ADCK3. Recognizes ADCK3 from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

Phospho-IGF2R (Ser2409) Antibody

CSB-PA973142-
EUR 335
Description: A polyclonal antibody against Phospho-IGF2R (Ser2409). Recognizes Phospho-IGF2R (Ser2409) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Phospho-IGF2R (Ser2409) Antibody

CSB-PA973142-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-IGF2R (Ser2409). Recognizes Phospho-IGF2R (Ser2409) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:1000, IHC:1:50-1:100

Phospho-NFATC3 (Ser165) Antibody

CSB-PA973276-
EUR 335
Description: A polyclonal antibody against Phospho-NFATC3 (Ser165). Recognizes Phospho-NFATC3 (Ser165) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-NFATC3 (Ser165) Antibody

CSB-PA973276-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-NFATC3 (Ser165). Recognizes Phospho-NFATC3 (Ser165) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-MAPK14 (Tyr322) Antibody

CSB-PA973394-
EUR 335
Description: A polyclonal antibody against Phospho-MAPK14 (Tyr322). Recognizes Phospho-MAPK14 (Tyr322) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-MAPK14 (Tyr322) Antibody

CSB-PA973394-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-MAPK14 (Tyr322). Recognizes Phospho-MAPK14 (Tyr322) from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

ABHD11 Antibody

CSB-PA973412-
EUR 335
Description: A polyclonal antibody against ABHD11. Recognizes ABHD11 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

ABHD11 Antibody

CSB-PA973412-100ul 100ul
EUR 316
Description: A polyclonal antibody against ABHD11. Recognizes ABHD11 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

TNFRSF1A Antibody

CSB-PA973584-
EUR 335
Description: A polyclonal antibody against TNFRSF1A. Recognizes TNFRSF1A from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

TNFRSF1A Antibody

CSB-PA973584-100ul 100ul
EUR 316
Description: A polyclonal antibody against TNFRSF1A. Recognizes TNFRSF1A from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

MARCH4 Antibody

CSB-PA973628-
EUR 335
Description: A polyclonal antibody against MARCH4. Recognizes MARCH4 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

MARCH4 Antibody

CSB-PA973628-100ul 100ul
EUR 316
Description: A polyclonal antibody against MARCH4. Recognizes MARCH4 from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, IHC;IHC:1:50-1:100

SLC9A9 Antibody

CSB-PA973659-
EUR 335
Description: A polyclonal antibody against SLC9A9. Recognizes SLC9A9 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

SLC9A9 Antibody

CSB-PA973659-100ul 100ul
EUR 316
Description: A polyclonal antibody against SLC9A9. Recognizes SLC9A9 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

FAF1 Antibody

CSB-PA973763-
EUR 335
Description: A polyclonal antibody against FAF1. Recognizes FAF1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

FAF1 Antibody

CSB-PA973763-100ul 100ul
EUR 316
Description: A polyclonal antibody against FAF1. Recognizes FAF1 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CNTN6 Antibody

CSB-PA973774-
EUR 335
Description: A polyclonal antibody against CNTN6. Recognizes CNTN6 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

CNTN6 Antibody

CSB-PA973774-100ul 100ul
EUR 316
Description: A polyclonal antibody against CNTN6. Recognizes CNTN6 from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

SIRPA Antibody

CSB-PA973893-
EUR 335
Description: A polyclonal antibody against SIRPA. Recognizes SIRPA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

SIRPA Antibody

CSB-PA973893-100ul 100ul
EUR 316
Description: A polyclonal antibody against SIRPA. Recognizes SIRPA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100

CCNB1 (Ab-147) Antibody

CSB-PA973969-
EUR 335
Description: A polyclonal antibody against CCNB1 (Ab-147). Recognizes CCNB1 (Ab-147) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

CCNB1 (Ab-147) Antibody

CSB-PA973969-100ul 100ul
EUR 316
Description: A polyclonal antibody against CCNB1 (Ab-147). Recognizes CCNB1 (Ab-147) from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC, IF;WB:1:500-1:1000, IHC:1:50-1:200, IF:1:100-1:200

Phospho-CXCR2 (Ser347) Antibody

CSB-PA974167-
EUR 335
Description: A polyclonal antibody against Phospho-CXCR2 (Ser347). Recognizes Phospho-CXCR2 (Ser347) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

Phospho-CXCR2 (Ser347) Antibody

CSB-PA974167-100ul 100ul
EUR 362
Description: A polyclonal antibody against Phospho-CXCR2 (Ser347). Recognizes Phospho-CXCR2 (Ser347) from Human, Mouse. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:1000

DGKA Antibody

CSB-PA974220-
EUR 335
Description: A polyclonal antibody against DGKA. Recognizes DGKA from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

DGKA Antibody

CSB-PA974220-100ul 100ul
EUR 316
Description: A polyclonal antibody against DGKA. Recognizes DGKA from Human. This antibody is Unconjugated. Tested in the following application: ELISA, WB;WB:1:500-1:3000

PCNA Antibody

CSB-PA974334-
EUR 335
Description: A polyclonal antibody against PCNA. Recognizes PCNA from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: ELISA, WB, IHC;WB:1:500-1:3000, IHC:1:50-1:100


We show that the former PS patients who developed RPS has raised fibronectin- and reduce the level of PAI-2 is already in the early / mid-pregnancy. This deviation is even more prominent in women with PV below normal pre-pregnancy, support the development of 2-step screening program for former patients to identify high-risk groups of women who may benefit from closer scrutiny.