Tag: pcram

August 7, 2020

Deficiency of plasminogen activator inhibitor 2 in plasma of patients with hereditary angioedema with normal C1 inhibitor levels.

Hereditary angioedema with normal levels of C1 inhibitor (HAE-N) is associated with mutations in Factor XII in 30% of subjects; However, the role of this mutation in the pathogenesis of angioedema is unclear.We are looking for evidence of abnormalities in the pathway of bradykinin bradykinin formation and degradation in the plasma of patients with HAE-N both with and without the mutation. Bradykinin has been added […]